Description
Decapeptide-12 (200mg) – Research-Grade Tyrosinase Inhibitor
Look, here’s the deal. You’re researching skin pigmentation. You know the target: tyrosinase. This 200mg vial of Decapeptide-12 is a precision tool for that job. It’s not magic dust; it’s a specific oligopeptide (sequence: Tyr-Arg-Ser-Aar-Lysd-Tyr-Ser-Ser-Trp-Tyr) built to interact with the tyrosinase enzyme pathway. The goal is to understand how to moderate melanin production in epidermal models. We stock it because the published data is compelling and researchers keep asking for it.
What Does The Research Say?
Think of Decapeptide-12 as a potential key for a specific lock. Studies suggest it may bind to tyrosinase, potentially inhibiting its activity. The objective is a observed reduction in hyperpigmentation in research models.
- Melasma & Photodamage Models: One 12-week study reported a 100% reduction in hyperpigmentation in approximately 40% of test models with standard tone. Models with severe (grade 4) photodamage showed improvement, moving to grade 3.
- Solar Lentigines: A separate 24-week investigation indicated complete clearance in about 38.5% of cases studied, with the entire cohort showing some level of improvement.
- Penetration: The native peptide has a lyophobic structure. Research into a palmitate-modified version suggests enhanced epidermal layer penetration while maintaining target activity.
The mechanism isn’t fully mapped, but the prevailing theory is direct enzyme interaction or interference with gene expression in melanocytes. Bottom line for your lab: it’s a compound with a defined target and a body of literature showing potential effect.
Specifications & Handling
You need the facts. Here they are.
- Purity: >99%
- Quantity: 200mg
- Molecular Formula: C65H90N18O17
- Molecular Weight: 1311.46 g/mol
- CAS Number: 137665-91-9
CRITICAL NOTICE
This product is FOR RESEARCH USE ONLY IN A CONTROLLED LABORATORY SETTING. It is a chemical tool, not a consumable. It is NOT for human or animal consumption, diagnostic use, or introduction into any organism. Handling is restricted to licensed, qualified professionals familiar with peptide safety protocols. By purchasing, you certify you are authorized to acquire this material for lawful research purposes.
Shipping: Orders placed by 12 PM PST ship same day. Sealed, stable temperature where required.
Price: $248.60
If your work involves tyrosinase and melanogenesis pathways, this is a primary research compound you should have on your shelf. The data is there. Do your own validation.




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