What You’re Getting

This is Acetyl Hexapeptide-3, commonly called Argireline. You get 200mg of high-purity peptide, sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2. Molecular weight 888.99 g/mol. It ships stable and ready for your controlled research environment.

Think of it as a precision tool. Its mechanism is well-documented: it mimics a portion of the SNAP-25 protein, which is involved in the SNARE complex that facilitates neurotransmitter release. In lab studies, this interaction has been shown to inhibit vesicle docking and the subsequent release of acetylcholine, leading to a reduction in muscle fiber contraction in model systems.

Documented Research Applications

The data is clear. Published studies on acetyl hexapeptide-3 focus on its potential to modulate neuromuscular activity and dermal structure in research models.

• Wrinkle Depth & Skin Mechanics: A 2002 study by Blanes-Mira et al. in the International Journal of Cosmetic Science found that a 10% acetyl hexapeptide-3 solution led to a 30% reduction in wrinkle depth in a specific model after 30 days. Research suggests it works by supporting the skin’s endogenous collagen production and extracellular matrix integrity while limiting contraction signals.
• Muscle Contraction Models: Research, including a 2013 pilot study in the European Journal of Neurology, investigated its adjunct potential in models of muscle twitching. Data indicated a trend toward prolonged reduction in twitching activity when used alongside certain neurotoxins, suggesting a stabilizing effect on neuromuscular inhibition.
• Skin Barrier Function: Studies note a correlation between acetyl hexapeptide-3 application and decreased transepidermal water loss (TEWL) in skin tissue models, indicating a potential role in supporting barrier hydration.

It’s a studied alternative to more invasive methods for researchers exploring dermal physiology and neuromuscular junction activity.

Specifications & Handling

Purity: >98% (HPLC)
Form: Lyophilized (freeze-dried) powder
Storage: Store in a cool, dry place (recommended -20°C for long-term stability).
Synonyms: Argireline, Acetyl hexapeptide-3, Argireline Acetate.

Important: This is a research chemical. It is not a drug, cosmetic, or dietary supplement. It is strictly for in-vitro laboratory analysis and experimentation. All information presented is for educational purposes within a research context. You must be a licensed researcher or qualified professional to purchase and handle this material. Handle using appropriate laboratory safety protocols.