Lipopeptide (Biopeptide EL) 200mg – Research Grade

SKU: Palmitoyl Hexapeptide-12 | Sequence: Pal-Val-Gly-Val-Ala-Pro-Gly-OH | Purity: >99%

This is Lipopeptide, also known as Biopeptide EL or Oligopeptide-34. It’s a synthetic fragment of elastin with a palmitic acid tail attached. That fatty acid chain isn’t just for show—it helps the peptide penetrate deeper into tissue structures for more direct contact with fibroblast cells. If your research involves skin aging, extracellular matrix (ECM) integrity, or fibroblast behavior, this is a key compound to have in the lab.

The core sequence (VGVAPG) is a repeat found in human tropoelastin. Because of this, it’s recognized by cells. The literature suggests it doesn’t just sit there. It appears to interact, influencing fibroblast activity. Think of it as a signal.

What the studies point to:

• Fibroblast Proliferation & Synthesis: Research indicates VGVAPG can stimulate fibroblast growth and may upregulate the production of key ECM components, specifically collagen and hyaluronic acid. It’s studied for its role in supporting the structural network of skin.
• Cell Migration: Acts as a chemoattractant. Fibroblasts move toward this peptide. This is crucial for research into tissue remodeling and repair mechanisms.
• Pigmentation Pathways: In vitro data shows potential modulatory effects on melanogenesis, with observed downregulation of key factors like MITF and tyrosinase in melanocytes.
• Inflammatory Response: May influence pro-inflammatory cytokine production (e.g., IL-6) in keratinocytes and fibroblasts. This interaction is relevant for studies on ECM preservation and MMP activity.

Specifications:
Molecular Formula: C38H68N6O8
Molecular Weight: 736.98 g/mol
Synonyms: Biopeptide EL, Oligopeptide-34, Palmitoyl Hexapeptide-12

Handling:
This is a raw material for laboratory research use only. It is NOT for human or animal consumption. It is NOT a cosmetic, drug, or dietary supplement. Handle with appropriate PPE in a controlled setting. You are responsible for knowing your local regulations and operating within your institution’s guidelines. By purchasing, you confirm you are a qualified researcher.

Logistics:
Ships same day if ordered by 12 PM PST. Sealed, desiccated, and shipped at ambient temperature. Full tracking provided.